
Each party member has a different playstyle for example, the anti-Joy crusader Ajeet's standard attacks are various Pokes that do no damage but provide guaranteed status effects on the enemy, and as such his only method of direct damage is through his special moves. Other party members use a variety of techniques for both offense and defense, and applying status effects such as poison or paralysis. In battle, Brad and some of his companions are able to use combination attacks using the "Dial Combo" system, allowing the player to press a sequence of keys to use powerful attacks like fireballs. There are thirty different potential companions in addition, all of them but Brad are susceptible to permanent death through either scripted events such as Russian Roulette or against certain enemies, who will occasionally use permanent-kill moves. The overworld features an assortment of settlements with shops and bars, where recruitable party members can often be found. Brad, and certain party members, are addicted to a drug named Joy that can drastically increase their power, but gives them withdrawals when they do not use it. Lisa features a combination of traditional turn-based RPG combat in a 2D side-scrolling overworld. Along the way, he is forced to make choices that permanently affect both his own well-being and that of his party members.

In Lisa, the player controls Brad Armstrong, a middle-aged man with a troubled past who journeys through the wasteland of Olathe in search of Buddy, his adoptive daughter. It also became known as one of the greatest sequels ever made. This game is widely considered one of the greatest RPG Maker games of all time, as well in the post-apocalyptic genre.

It is the second game in the LISA Trilogy. Lisa RPG Wiki view template page Lisa: The Painful is a post-apocalyptic side-scrolling RPG game created by Dingaling Productions.
